2021 Early Detection Seminar Series
Seminar & Discussion: 11:00am - 12:00pm, PT
The Canary Center at Stanford for Cancer Early Detection is committed to fundamental discovery and translation of novel early cancer detection and prognostication strategies. We have brought together scientists, physicians, and engineers to think outside the box to create new solutions for cancer early detection. The Canary Center hosts a seminar series, CEDSS, that presents seminars highlighting new research in Early Cancer Detection. These seminars are open and free to everyone in the Stanford community.
Note: This seminar does not run through the Summer months.
October 12, 2021
The First Cell: A new model for cancer research and treatment
Azra Raza, MD
Chan Soon-Shiong Professor of Medicine
Director, Myelodysplastic Syndrome Center
Columbia University Medical Center
Cancer research continues to be predicated on a 1970’s model of research and treatment. Despite half a century of intense research, we are failing spectacularly to improve the outcome for patients with advanced disease. Those who are cured continue to be treated mostly with the older strategies (surgery-chemo-radiation). Our contention is that the real solution to the cancer problem is to diagnose cancer early, at the stage of The First Cell. The rapidly evolving technologies are doing much in this area but need to be expanded. We study a pre-leukemic condition called myelodysplastic syndrome (MDS) with the hope that we can detect the first leukemia cells as the disease transforms to acute myeloid leukemia (AML). Towards this end, we have collected blood and bone marrow samples on MDS and AML patients since 1984. Today, our Tissue Repository has more than 60,000 samples. We propose novel methods to identify surrogate markers that can identify the First Cell through studying the serial samples of patients who evolve from MDS to AML.