SunCollect MALDI Spotter-Sprayer
The SunCollect is a versatile instrument designed to operate as both an HPLC effluent touch-off spotter for MALDI target spotting and a micro-fraction collector for collection of HPLC effluent onto MALDI plates and into multiwall plates. For MALDI imaging mass spectrometry, The SunCollect offers a simple add-on accessory that allows for spraying protease and matrix solutions over the surface of a 2D tissue section by pneumatic atomization. Delivery of a homogeneous matrix layer is very reproducible and results in a very consistent matrix thickness. Depending on the matrix used, an initial light layer facilitates the formation of seed crystals that subsequently afford in a high degree of matrix homogeneity. System variables include matrix flow rate, needle speed, and number of layers. These can all be separately controlled over up to ten layers of matrix addition. The spraying software is simple and allows for quick changes to the speed of the spraying needle, number of tissue samples being sprayed, and the number of layers that will be placed over the tissue sections.
Leica CM1850 Cryostat
The Leica CM1850 cryostat design incorporates emphasis on power savings, increased efficiency and operator safety. The result is a versatile cryostat with an optimized cooling system, rapid specimen freezing and smooth specimen orientation for the high-quality sectioning demanded in routine histology and clinical pathology. The illuminated cryochamber is easily accessible through a large heated sliding window. Ample space is provided for convenient specimen handling. Smooth surfaces inside ensure safe and easy cleaning. The microtome is protected by a slot cover to allow easy and safe spray disinfection. The smooth specimen orientation with automatic centering and zero notch features outstanding handling capabilities for fast and precise sectioning.