Canary Center at Stanford
for Cancer Early Detection  

Proteomics Core Facility

Stolowitz
Mark Stolowitz, PhD
Director, Proteomics Core Facility

CC@S Proteomics Core Facility

The Proteomics Core Facility in the Canary Center for Cancer Early Detection at Stanford is a state-of-the-art mass spectrometry resource dedicated to the discovery and verification of blood-based protein biomarkers. The core facility has acquired the recently introduced AB/Sciex 5800 TOF/TOF mass spectrometer in support of this effort.

The focus of the facility is the development and implementation of a high throughput biomarker verification platform that exploits magnetic nanoparticle facilitated immunoaffinity capture as a prelude to mass spectrometric biomarker quantification.

The facility has also implemented an LC-MALDI workflow utilizing an AB/Sciex Tempo LC-MALDI Spotter and the 5800 TOF/TOF System to supplement the ongoing biomarker discovery efforts supported by the Canary Foundation at the Center as well as elsewhere. 

GenoLogics’ Proteus bioinformatics platform permits the management of multiple biomarker discovery and verification studies, and enables core facility end users to access raw data and results via a web-based client server located in the Center.

Ken Lau
Ken Lau
Life Science Research Assistant, Proteomics Core Facility

 

Uma Kota
Uma Kota, PhD
Postdoctoral Scholar, Radiology

AB Sciex 5800 TOF/TOF System [Applied BioSystems PDF], [Applied BioSystems Video]

Tempo LC-MALDI Spotting System [Tempo MALDI PDF]

ProteinPilot 3.0 [ProteinPilot PDF] and GenoLogics Proteus [GenoLogics PDF]

Link to Proteomics Core Equipment Floor Plan

 

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